I have a S&W 325 Thunder Ranch that I had machined to accept .460 Rowland. Of course, it took me over a hundred dollars worth of ammo to figure out that it doesn't like the large rifle primers that Buffalo Bore uses for .460 Rowland. Large Pistol primers in the same caliber, however, it will always ignite. It's a handful, but I hope to carry it this year when I head to North Idaho.
But if someone would ever ask me if I wanted to trade for a Dan Wesson 7460 Pistol Pack, I would sprain my shoulder reaching for it so fast.