I have a Gen 4 in 10.5 and 16 inch barrels. I have not had any issues as long as the ammo is SAMMI spec. I've had some cheaper ammo jam in the chamber because it was out of tolerance. I'd stick to newly manufactured rather than reloads.
I shoot them suppressed 99% of the time. Never had a problem with extraction. The chamber does get dirtier than I expected from a piston. I'm not sure if it's the E2 leaking a little extra gas or from the back pressure from the can. I am glad mine are NP3 coated though, clean up is significantly easier. As an FYI, the BCG and the upper channel will discolor over time with usage. I talked with Robar and they said it's normal and not to worry about it. The NP3 coating is still okay.
I am definitely glad I got the Gen 4 over the 3. The ergonomics of the bolt catch / release is nice. It's better (IMHO) than trying to find a BAD lever that will work with the POF lowers. The Magpul ones don't. The E2 is an added bonus. If it does extend the life of the extractor so much the better.
If it was me, I'd only get a Gen 3 if it was significantly less expensive than a Gen 4. Looking forward, everything POF makes will be Gen 4 oriented so if you want to future proof .........
Btw, I replaced the regular POF trigger (which is awesome in and of itself) with their EFP2 trigger. It's even better!