Honda Pilot is a mid-sized crossover (SUV body on car chassis from the Honda Accord) and a Toyota 4Runner is a midsized SUV on a Land Cruiser chassis. I know there is some confusion on what consititues a crossover vs. an SUV.
Definition: "A crossover is based on a car's platform, while an SUV uses the chassis of a truck. The result is that crossovers use "unibody" architecture, meaning the body and frame are one piece, while SUVs use a "body on frame" design. In that case, the body is built separately from the frame and placed together later."
So first thing you need to decide is if you want a midsized Crossover or a midsized SUV?
Do you want 4x4 or 2 wheel drive?
I've always read that the sweet spot for car value depreciation is 3 - 5 years.