The good:
Awesome outdoors opportunities. Enjoy fishing and hunting? Welcome to paradise. You have tons of private land right off your doorstep. There are wilderness areas in Oregon bigger than some east coast states. You drive 45 minutes outside of Portland and you are literally in a designated wilderness area. I saw three people drive by when I was driving into the place I deer hunted last year and saw exactly zero people while I was stomping around the woods deer hunting. Try that back east on public land. Really nice mild weather (although this year was hot). People are nice for the most part. No sales tax is nice on things like vehicle purchases. Some industries pay really well. Medical, government, and engineering seem to bring in the big bucks. You've got the Pacific ocean in driving distance. Great places to eat. Good local breweries and wineries...even if they do think a but much of themselves at times. Public shooting is simply getting in your vehicle, getting out on a national forest road, and finding a safe place to shoot. Gun laws are pretty good. No more FTF's w/o going through an FFL and the state handles the background checks, so it can be a little slow at times. It's not that bad though.
The bad:
Welcome to tax hell. Property tax and state income tax are obscene. The state alone takes a healthy 9.9% cut out of every paycheck for income tax. The state government is running on armature hour. It seriously is like a small town government is running the entire state. The urban area seems very detached from the needs of the rural agricultural areas. We recently lost an exporter that was 10% of Oregon's net tax revenue. That was an enormous hit to Oregon's agricultural industry. Lots of farmers lost an entire years crops that were sitting on that ports docks and now they have to ship most of their food up through WA cutting into their margins even more. Government at the time was more worried about the governor's girlfriend. The tax system is not favorable to big companies moving in, so there is little growth in that arena. Housing prices are really high. I'm not sure what MO's housing market is like, but I can compare it to Nebraska's. A 150k house in NE is a 350-380k house here. Small little town homes are 180-200k. The bikers are militant, they will blow through stop signs, be riding up a hill on a blind corner, in the middle of the road, going five MPH on a 45 MPH road, on a foggy morning, and not give two fucks. There is no such thing as city planning. Traffic gets congested very easily for no apparent reason.
My wife and I are leaving after almost two years here. We are from the Midwest and prefer that lifestyle a little more, but we feel blessed to have the opportunity to have lived out here for the time we have. It's a great place to live. Like everywhere it has it's pros and cons. While Oregon is ultimately not for us, I'd come back here to vacation in a heart beat.