If you use Excel be sure to BACK IT UP! Print it out and keep it in your book.
Hard disk drives fail. Eventually, they all fail. It is just a matter of time.
Excel is what I use, too. It isn't just the tables it creates, it's the plots. The plots take all that numerical data and condense it into something you can look at and understand. I put in the load data, the chronograph data and the target information. Don't forget to describe the rifle used, the date, the environmental conditions, everything you can.
I have even started to photograph the primer end of the cases and include copies of the photos in the spreadsheet. I make a 3X5" card describing what's in the photo (which cases are which) and the card is shot in the photo of the cases. The cases get put back in the box, primer end facing up, each load in its own row (or column) within the box.
Keep your targets, too. Annotate them with comparable information.
Honestly, I don't think anyone can do this for you. What you do, how you do it, is entirely up to you. Have fun doing it.
I hope this helps in some way.