I put a few hundred rounds through mine in the beginning. I ran into trouble dry firing it though. The firing pin made an indentation into the face of the chamber peening it. It would not load any more rounds. I tried to fix it myself and filed the face of the chamber. It fixed it, sort of, but was not longer the reliable pistol it was when new.
I sent it back to Ruger with explanation to what I had done, fully expecting to have to pay for the new barrel. Five days later I got it back with a new barrel, firing pin and something else maybe. They tested 40 rounds through and had noted that it was working again. That's nice customer service. All free - even after my attempt to fix it myself.
So I wouldn't worry too much if it fails at 50k or 100k. Just tell them and they'll give you a shipping label, make it good, and send it back within a week.
How can you beat that?