I have XXL palms, and Medium/Short, stubby fingers.
Favorites:
Ruger SR22 pistol -- Feels great with either backstrap...I love the grip, angle, texture, etc.
Glock -- gen4 19 and gen4 17 (I usually get them stippled which makes them feel a bit smaller--a grip reduction would feel even better).
Glock -- 43 and 42 (both feel GREAT, though I end up using grip tape or a Hogue Jr to get a better grip on them).
Kahrs -- P9/CW9 (again with the Hogue--but hate the trigger and reset).
I'd love to hold the VP9, SW MP9, etc., with the smallest grips and side panels or whatever, but most gun shops ONLY have the medium installed--so I don't know if I like them.
Sadly, all of the polymer 45s are TOO thick for me--though I may someday get a 45 M&P down the road, since it has to be more bearable than Glock (though I think my next pistol will likely be a gen4 G22 with a ported barrel).
I hate: any wide grips side-to-side, but even being long front to back is horrible (like the Shield, which is otherwise a small grip, but long front to back).