I have built a couple of the 5.45 AR's. It depends on what your reason is for building it, but the ammo can still be found cheap enough to warrant a 5.45 build IF you shoot enough.
I personally think the time has passed on the 5.45 AR platform, but I am sitting on a decent stock of ammo and I built these a few years ago.
I have both ASC mags and modified magpul mags and both have worked very well for me. My favorite are the modified magpul mags.
There have been many stories of folks that have had some issues with a 5.45 build, but I think these are the vast minority. I have built 5 of them and had never had any major issues. I had one that was under-gassed and had to open the gas port a bit and I also received some bolts from Ballistic Advantage that had very tight extractors, but a tiny bit of 'smithing on those and they worked flawlessly,
If you are for sure that you want to build a 5.45, no reason really not to, but just keep in mind that cost of the build when factoring in how much money you would save. It used to be that you could save the cost of the conversion with two tins of ammo (2,160 rounds) but lately I would think that it would probably be double that.
Still it is really fun at the range to see the look on people's face when you tell them that you are shooting a 5.45. I have had more than a few folks try to convince me that I meant 5.56.