Here are facts about your upper: The bore diameter is slightly larger, and your sights are calibrated for .223/5.56. With that said, the bullet won't go where you used to aim and it will drop differently. How differently? Well you'll just have to test for that. For me, at 25 yards, I aim just below the 300 tick of my optic. It hits that area every time. Comparing to a 5.56 round, it hits the 300 mark at that range so I am nearly identical.
What I learned is that if I shoot the .22 dropin, I can shoot it all day long. No clogging, nothing. The gas tube can be blasted out by simply shooting a few .223.
On the flip side, I learned that shooting cheap Tulammo and then shooting the drop in is disastrous. For some reason Tulammo clogged up my barrel, I then put the conversion in and rounds were shooting wildly all over the place (talking about 5ft off in random directions). I had to clean the barrel for days. I'm still shooting Tulammo and the drop in kit, but I'm just not doing it together.
If you shoot the drop in conversion kit, and then shoot a few .223 afterwards to clean it, you should never encounter a problem.