I had a nice little tutorial / discussion thread on using single on camera flash posted here.
Zero fucks were given. Pictures and examples were included.
Most of the basics have been covered. I prefer to use a single flash more as a fill rather than a primary source of light, but well diffused (bounced off of something) it can also be a good primary.
People are giving you aperture and shutter and ISO settings - they're good starting points but as you should already know this each situation is different.
The single best tip I can give you is this: Control all aspects of the light in your scene. Remove as much as you can, add back in only what you need to light the picture.
This was lit with a single on camera flash (this picture has been approved for use in technical discussions, even though it's walking the line of BOTD):
Is it the best picture? No, her expression is dreadful, and the composition and overall feel of the picture could use some work. That's not the point. The lighting is fucking AWESOME.
This was one of the test shots I did to see if I could get the light to do what I wanted it to do. The others..well, they'll never be posted.
Exif info looks something like this:
D7100
17-55 f/2.8 @ f4
30mm
1/200
ISO100
I don't recall what the flash power was set to, I'd bet it was on TTL +1 but I can't 100% guarantee that.
Here's how I did it:
I don't have any specific experience with your flash, but I suspect it plays by the same rules as most others.