I've found the Leatherman Juice S2 just about the perfect compromise size for a multi-tool. I have 15+ multitools currently, ranging the full spectrum of sizes, from most manufacturers,
and have had others over the years. That's not counting the SAKs with pliers.
The Juice S2 is large enough for my largish hands to use easily, but small enough that women are able to use it comfortably. My wife has no problem with it, &
we've given one to a couple of cousins when they went off to college, and both girls loved them. It's also large enough, and robust enough, to use moderately hard, as well.
And, it's one of the rare multitools that carries easily in a pocket, due to it's rounded corners.
I pocket-carried mine daily for several years as a computer tech, and it's still in my weekend EDC bag. A Juice S2, or one of it's siblings on the same frame, would be my recommendation
for any with smaller hands.
I do not yet have a Skeletool, but like what I see in them. I have a couple of Leatherman tools that use those proprietary bits...and admittedly, they gave me some pause when
I first got them, but in actual use, they're just fine, and I really like the versatility they add.
Good luck in your search.
David