OP, I try to vacation with my family in the Tampa area (clearwater-st.Pete ) yearly . We always fish w/o a guide and just rent some nice kayaks for 3-5 days . I always contact Wyatt @ Florida Kayak Outfitters . This guy has delivered the kayaks right to the hotel,condo or house that we've rented. We mainly fish the inter-coastal waterways for anything that will bite (red fish,snook,snapper) . Hit a tackle shop and get some shrimp , also dont be afraid to try a 3" swim bait on a 1/4-1/2oz jig head . Med action 7' rod 8-10lb flouro . Fish near structure (bridges,docks,mangroves) .
Good luck!