I have what you are considering in NE MS.
First. did you notice the posts for the most part mention price..You won't be able to keep the doors open without a realistic markup. Especially if a brick and mortar paying rent or loan payments for the building.
The items wanted by people at a given point and time is ever changing. Making it difficult to get said items at a price that can be sold for profit. There will always be the person that can get this or that on the net cheaper. You'll have to just be honest and say I can't do that. Distributors are even having a hard time getting some things which makes it hard for the little guy.
Not trying to discourage you by no means.
Example, customers tell's another WalMart has the BoreSnakes cheaper. He tells the guy he had rather pay the $1.00 more here than the other place. It's 17 miles to that WalMart, some will drive there and back to save that $1.00. Never considering the costs involved [gas, insurance, wear]. Old saying "penny wise, dollar foolish" fits.
Everyone will have their hand in your pocket, County, City, State, and Federal before you even open the door. .
You know your area and whats needed. Better qustion is can you and your buddy fill that need and make a dollar? It takes capital to start, if borrowed you are in a hole already, especially if you are renting a location as well.
Just some things to consider if serious about this.