Not the ACOG-
Put it on the EO tech. (use something weak like low or medium strength loctite- something that doesn't need to be heated to dissassemble.)
Every screw (including ACOG base to houseing if you are changing one out) that goes on a rifle needs loctite.
That doesn't include [obviously] the barrel nut, or the pistol grip screw, but some guys like to do stock nuts in absence of peening them on.
I haven't done the peen or loctite yet and haven't had one come loose (I just torque it heavilly; like 30+ft lbs.)
Ace hardware, advanced auto parts, NAPA, etc. Those guys should carry loctite. Sometimes Walmart, and sears tool centers