Well, first of all it would be the WORST movie ever made from a Clancy novel, due to hollywood's #1 commandment: 'Thou shalt not offend Liberals or impugn their Causes...' (something Clancy does alot), and the #2 commandment 'Every character in an action/drama movie must be under 40. If they are over 40, they must be a side character, or a bad guy'...
So:
1) The bad guys would not be ultra-left-wing enviro-whackos who want to kill the whole world and start over (like Hugo Drax from 007: Moonraker), they would be greedy corproate types playing god to make money (basically the biotech version of Enron)...
2) All of the characters ages would be changed to make them more eligable to be played by Broznan/DiCaprio/etc... Clark (who is in his upper 50's, married, and is Chavez's father-in-law would be in his late 30's, with a 'Rambo's boss' type attitude (lone wolf/etc). Chavez would be a '007 wannabe', complete with the token 'girlfriend-of-the-hour'...
3) All of the stuff about R6 being created by President Ryan (who, if we follow Afleck, is too young to be Prez yet anyway) because of his brush with IRA terrorists (Patriot Games) to fight international terrorisim at an above-the-law level would be skipped.
4) The 'terrorists' could not be communists or arabs (IIRC, in R6, they were mostly neo-communist groups, and they were re-activated by a former KGB agent who was working for the bad guys (without knowing why, of course)). They would have to be re-cast as neo-Nazis, drug dealers, and 'militia' goons, or maybe even members of the US government trying to get re-elected...
5) The bio weapon would be hidden in a cigarette vending machine, instead of a maintanance closet...
YEACK!!!!!!!!
As for race, Clancy doesn't mention it in 'Without Remorse' (aka 'The Clark Book')... I never gave it a thought... The only perminant character who's race is mentioned at-point (apart from Ryan being Irish/white) is Robby Jackson (Tomcat pilot (Admiral in the later series)) being black...