Quoted:
without the lead in 100LL, you end up with avgas that is about 94 octane, which would be equivalent to about 96 octane car gas.
using modern computer-controlled spark timing and mixture control, this 94 octane unleaded avgas has been used without ill effects in high-output aviation motors.
the problem is getting the FAA to approve the use of modern ignition systems in aircraft. despite the 30 year history of excellent reliability, the feds are still worried about electrical system failure and the loss of ignition. so we are still stuck with 1930's Farmall tractor ignition technology.
And the cost of such things that are only used by the VERY small market of general aviation. Therefore, you are paying out the nose as there is no economy of scale.
There is absolutely no technical reason why there aren't full retrofit kits for every O-360 engine out there that will eliminate that stupid mixture knob. Safety would be improved, as reliability would be increased since the solid state ignition modules are very reliable and light. The systems could even be 100% redundant with dual "mags". Efficiency would increase, as you could run at the right mixture setting all the time. Temps would even out some, as fuel metering would be much better. Just imagine, a key, a small diagnostic reader for your engine linked to a simple ECM, a throttle, and a prop control. No more mixture.
The only reason they don't exist is the liability and the paperwork. The market isn't big enough to warrant the investment in the paperwork.