My old targus backpack has just about had it, one of the backpack straps is half torn off, it's a mess, so I need a new bag.  I am pretty sure I want another backpack since I haven't found a single strap bag I liked at all.  I have browsed through worstbuy and won'tsons leather, and tried searching online but so far haven't found anything I like.  A problem I am having is search overload.  No matter what search terms I choose, there are either 12 million hits or zero, and I am no closer to my goal.  So, I am starting with a (relatively) clean slate and asking for suggestions from arfcom.  

Loose requirements:
Prefer integrated padding rather than a sleeve for the LT, and more padding is better than less.
I carry a fair amount of stuff with my laptop, some tools, etc. so I need pockets/organizers in addition to just the laptop carry.
Must be at least a little water resistant - I am not taking it diving, but I don't want to have to panic if I feel a raindrop or two.
Would like to carry a 32oz Nagene bottle.
I have a fairly small laptop now, but have been thinking bigger, so would like to fit a 17" or smaller
This is a big one: Must have worthwhile shoulder straps and padding.  So many of the packs I have seen are just awesome until you look at the strap and pick them up.  Then they suck.  What I am envisioning is at least quality 3 day pack level shoulder straps.

So, what do you use, and what do you like or dislike about it?

http://www.bhphotovideo.com/bnh/controller/home?O=&sku=1005550&gclid=CKiuxZWdnMMCFfNZ7AodV10ASw&Q=&is=REG&A=details

Good overall bag.  Lots of space.  Many compartments.  Decent quality shoulder straps.