If you're looking for "optimal decibel reduction", as you say, than go a bit beyond 6".
Can 6" aid in suppression, yes.
Will it yield optimal results, no.
Look more towards the 8" mark. Oodles of Form1 designs out there matching your intentions.
Ti won't hinder performance, but will reduce weight, so look into these parts. Just understand, Ti is going to drive your cost up so get a serious budgetary number together. Also, wait times are at a year, right now, so even saving $30/month will get you a respectable budget by the time you're approved.
Despite what the previous poster said, Aluminum is used everyday in silencers all over the world, even for magnum calibers. This being said, they're designed and made by manufacturers. Businesses that have designed and tested, failed, then redesigned and retested. It is not for the inexperienced home builder, especially not with the current retail parts available. One of the main reasons it isn't used in the US is the hoops people have to go through to buy one. The majority of us look at them as a lifetime purchase. Around the world, they're off the shelf items.
One more thing. You don't need a plan or design to start your Form1. All you need is caliber and length, and even those can be amended (yes, caliber can be changed if the making has yet commenced). Put down 30cal and 10". If you build it to 7" just send the ATF a letter stating the permanent change. (after you've been approved)