Quoted: OK, I'll bite. What is a RIFLE caliber round supposed to do at 750 and what round does what it is supposed to do? Does what a rifle round is supposed to do, I mean.
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Rifle calibers "do" significant temporary and permanent wound cavities, but are highly dependent on velocity,
and bullet contruction/design. Change one, or the other, or both, and you significantly detract from their performance in tissue. It's pretty simple. If a 150gr projectile, which may be devastating at 2400fps... will do anywhere near the damage when traveling 1100fps, like at 800yds. It wont fragment, deform, etc. A quality designed pistol round of a similar weight/velocity will like have a better effect.
Now, you cant shoot people with a pistol at 800yds.... so a hit is still a hit. This is why the 300WM or 338's are better long range weapons.... or, of course, the 50BMG. A bigger projectile, moving faster.
If you are gonna throw a rock..... throw the biggest rock, as fast as you can.