Friend has his Amsec (a good one, not the cheapest model) beaten on by the people who broke into his house, they didn't get in, but neither could he. Took the locksmith 3hrs to get into it.
As someone mentioned, they are pretty much only for fire protection and to slow down theives... You want a monitored alarm w/ cell back up, also try to put the safe someplace that doesn't make it easy for someone to move or work on (ie: just up against a wall.) I have mine in the most PITA room to get it into and it's in the closet, it took time and a lot of bitching to get it in there... I also replaced the room's foor with a solid core door, tougher strike plate, and better frame, plus added one of those punch code lcoks (like you see in office/industrical buildings.) The point is to really slow people down.