Yes, it is possible to eventually come off meds., but DO NOT stop taking meds on your own. If your present DR. was not interested in trying to get you off meds., find another DR.. Don't experiment without a DR., HBP can quickly lead to a stroke/heart attack. I'm on HBP meds, but mine is hereditary(SP). I tried losing weight, eating good, etc., but my pressure remained very high. So I'm on life long meds..