Speaking as the owner of 4 10mm guns and 2 .40 guns.--
1. The 10mm is close, in it's hottest factory loads to a .41 mag. It does exceed several of the .357 factory loads.
2. The .40 basically came about when the FBI wanted to download the 10mm due to recoil concerns. I agree with what the designers of the .40 did--why down load a large cartridge in a large frame handgun when you can make a smaller cartridge in a smaller frame handgun?
3. I still wouldn't use the 10mm for hunting--my Smith 10mm's (pre-sellout of course), Glock 10mm and Delta Elite are not what I consider accurate enough for hunting handguns (the round itself is OK, just the guns aren't 50-100 yd rounds). I would prefer a Ruger Super Blackhawk in .44 Rem. Mag. as a hunting handgun.
4. For self defense, I think the .40 is a little better, just due to the more manageable size (I have "medium" sized hands) of the guns (Sig 229 and Glock 22). The 10mm will more than do if you practice with it.
5. For fun, shoot a Winchester Silvertip or Norma round out of the 10mm. Nice size fireball from the silvertip and both have a pretty good recoil for an autopistol (not as much as a .357mag, but definitely more than a .40, 9mm or .45).
I think the IDEAL reason for a 10mm would be in a carbine. Then it would be practical to have a pistol in the same caliber. I would love to see a caliber conversion for an UZI, MP-5, AR-15 rifle in that caliber (with CHEAP, RELIABLE mags--the conversions I have seen have a reputation for being unreliable and/or expensive mags).