Hit Calguns, they had an argument of sorts about this about a week or two ago.
Definitely DO NOT get a 50BMG upper and put it on the lower receiver before the receiver has been added to the named "assault weapon" list. In the eyes of the law, that lower receiver in combination with that upper installed will be a 50BMG rifle and have to be registered as a 50BMG rifle.
You can only register a 50BMG if you bought it/owned it prior to Jan 1st 2005, that is not the case with your lower so you cannot legally register it as a 50BMG. If you put a 50BMG upper on the lower receiver you will in effect be manufacturing a 50BMG rifle, AFTER the ban which is a no-no.
Now, if you wait until the lower is added to the uber evil "assault weapon" list. You MAY potentiall be able to put a 50BMG upper on it.
The arguments on calguns are even questioning whether it would be legal to add a 50BMG upper to one of the receivers after it has been granted AW status and you have legally registered it, they still question whether it would be viewed as creating a 50BMG. This is even though it is well recognized that a rifle already registered as an "assault weapon" does not need to again be registered as a 50BMG.