Lee set up to keep tooling costs down, brass, WC 872 powder, CCI 35 primers, pull down bullets cleaned and run through a sizer, and you will be in the black before you have reloaded 200 rounds; over buying loaded ammo at close to $5 a pop instead.
Now if you are going to venture into making your own 50bmg bullet (swagging) then here is the desision of if you are going to go with a lee press on the inexpensive side to just reload the cases, or do you need a stronger press instead. Truth is, most don't push the rifle to 1K (only a few hundred yards at most), so easier to just produce solid brass bullets on a small CNC'd mini lathe out of round brass stock instead.
Or, you can cast for 50bmg, to end up with PC gas checked bullets instead. There not going to shoot at tight as solid or jackets bullets, cut cuts the price way down on the cost of the bullets itself when you are just moving say refrigerators or engine blocks around down range instead.