You could mix all three powders together and shoot it. You could put 10 grains of 4F in the bottom of the chamber and then put another 20grs of 1.5F on top of it. Call it a Duplex load. You're not going to hurt anything.
It's just a matter of how slow or fast do you want to shoot.
I bought 10 pounds of Aliant Black MZ substitute BP a couple years ago for $9 a pound. It has no Fg granulation. Reading around the web, it likes to be compressed. I found it doesn't measure well out of my 2 powder flasks. I'll keep using it till it's gone.
My preference is Graf's Scheutzen 3Fg BP. I shot this group with it a few years ago, standing, 2 hands at 21 ft. Group was shot with 30gr of powder, felt wad, Bore Butter, and a .454 diameter Hornady ball.
I find lube under the ball, over the wad, puts the lube where I want it - down the barrel instead of all over my hands / the outside of the gun.
It's not a hard and fast rule though.
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