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AR15.COM
4/15/2008 1:09:06 PM EDT
Simply amazing read.  Article and Video here
4/15/2008 1:11:33 PM EDT
[#1]
Wont that turn everyone into zombies that cant go out in the sun?
4/15/2008 1:12:20 PM EDT
[#2]
I remember reading this in popular mechanics a few years back as to what to expect in the "War on Cancer" within the next decade.

Amazing.
4/15/2008 1:12:31 PM EDT
[#3]

Quoted:
Wont that turn everyone into zombies that cant go out in the sun?



Everybody except for one guy, who works for the Army and lives in New York.
4/15/2008 1:12:35 PM EDT
[#4]
I saw this segment.  That's amazing.  The crappy part is that it will take 4 years of studies to make sure that it works.
4/15/2008 1:16:39 PM EDT
[#5]
It sounds like Royal Rife all over again.
4/15/2008 1:18:27 PM EDT
[#6]
wait... i saw this in a movie not to long ago...
4/15/2008 1:19:05 PM EDT
[#7]

Quoted:

Quoted:
Wont that turn everyone into zombies that cant go out in the sun?



Everybody except for one guy, who works for the Army and lives in New York.


Technically, one percent of the population.

Only, most of them get eaten.

4/15/2008 1:20:51 PM EDT
[#8]
This topic has been posted before; not this exact article, so it isn't a dupe. My response is the same as before. Sorry to rain on everyone's parade, but killing a single, solid, localized tumor isn't exactly a "hey, we've cured it" victory. The trick is targeting the particles to the cancer cells if it's metastasized, and they aren't any closer to that goal than any other research group.
4/15/2008 1:20:58 PM EDT
[#9]

Quoted:

Quoted:

Quoted:
Wont that turn everyone into zombies that cant go out in the sun?



Everybody except for one guy, who works for the Army and lives in New York.


Technically, one percent of the population.

Only, most of them get eaten.



oops, I forgot that part.
4/15/2008 1:23:33 PM EDT
[#10]
I've done some work with a Biotech startup that was working on this type of technology. It's utterly amazing and very promising but a long way off. Plus many more years of trials and FDA approvals and still not a magic bullet.

By the way, the work I was doing was in 2001-2002 so it goes to show you it takes a long time since they are still talking about this as very early stage stuff.
4/15/2008 1:24:26 PM EDT
[#11]

Quoted:

Quoted:
Wont that turn everyone into zombies that cant go out in the sun?



Everybody except for one guy, who works for the Army and lives in New York.


Don't forget that Brazilian chick and all those people in Vermont.  
4/15/2008 1:25:21 PM EDT
[#12]

Quoted:
This topic has been posted before; not this exact article, so it isn't a dupe. My response is the same as before. Sorry to rain on everyone's parade, but killing a single, solid, localized tumor isn't exactly a "hey, we've cured it" victory. The trick is targeting the particles to the cancer cells if it's metastasized, and they aren't any closer to that goal than any other research group.


Its a start.
4/15/2008 1:27:02 PM EDT
[#13]
it looks like a terrific idea but if the metallic nanoparticles heat up anything that surrounds them then wont all the free nanoparticles that are still floating around in the bloodstream not attached to tumors randomly damage the rest of the body.

There is going to have to be a way for the nanoparticles that arent connected to the tumor to be expelled from the body before the radio waves are sent. Hopefully they can be peed out or filtered out with some kind of blood filtering machine.
4/15/2008 1:27:09 PM EDT
[#14]
Something similar to this was on TV last night- Dateline or something. About the time it came on the dinner bell rang.

Inventor may have breakthrough in killing cancer cells
Inventor from Erie, P.A. teams up with leading cancer center.
The work has been quietly been going on for the last three years in a no-frills laboratory in Erie, Pennsylvania. Inventor, John Kanzius, working with Jim and Charlie Rutkowski, have been perfecting a device that will kill cancer cells with a radio frequency.

This humble workspace could soon become the epicenter of one of the most stunning scientific breakthroughs in cancer treatment in years.

Using the Kanzius RF machine and special nanoparticles, it appears that cancer cells can be targeted and killed without harming the rest of the body.

This is a deeply personal mission for John Kanzius. He is struggling to beat leaukemia. And he knows firsthand how tough standard treatments like chemotherapy and radiation can be on the body.

Kanzius told Channel 3's Mike O'Mara that, "If this ends up working they way it looks, it really could be the holy grail of cancer research."

The entire city of Erie is buzzing about John's invention. Two weekends ago, thousands turned out for a motorcycle rally called "Roar On The Shore". All the money is going to help John's cancer research.

Ralph Pontillo is the head of the Erie Manufacturers Association. He is proud that his city can help the Kanzius project.

"It's amazing, said Ralph, "that in the very near future someone is going to stick a pin on a map and say this is where cancer was cured. And that pin is going to be Erie, Pennsylvania. That blows your mind and that is inconceivable."

Former Erie Mayor, Joyce Savocchio, said "there are nights that I think about it and I can't go to sleep. It just enfolds you that you are on the brink of history and something so enormous that you can't imagine it."

The excitement is not limited to Erie, Pennsylvania. In Houston, Texas at the MD Anderson Cancer Center, a team of scientists believe that John Kanzius has the key to something extraordinary.

MD Anderson is one of the most respected cancer centers in the world. 79 thousand cancer patients were treated at the huge campus in Houston last year.

Doctor Steven Curley is leading the research team at MD Anderson. Dr. Curley is the author of over 110 publications and 30 book chapters, many dealing with the treatment of patients with hepotocellular cancer, gallbladder cancer, bile duct cancer, or liver metastases.

Curley is brimming with cautious optimism.

"If we can come up with ways of delivering these particles to the cancer cells, but not to normal cells," Curley said, "this treatment will work. There's not a doubt in my mind. Any kind of cancer, anywhere in the body!"

Doctor Curley's team is ready to publish their first results using laboratory animals. So far, the targeted nanoparticles and the Kanzius RF machine have passed every test.

"There is a great deal of work that has to be done", said Curley. "However, I suspect once the manuscripts are published, there's going to be a real rush of excitement about this whole process. I've already warned John to get ready because the floodgates are about to open."

Kanzius wants to make sure his invention does not get sidelined by an unsympathetic corporation that might not want see an effective treatment on the market.

Said Kanzius, "venture capitalists, big pharmaceuticals that might want to buy this to tempt me and stop the research, not going to happen. There is no amount of money that can buy me off. You can not put a price on a human life."

When the revolutionary treatment is ready for human clinical trials, you can bet that Erie, Pennsylvania will go to the front of the line. And why not, since the inventor lives just a few miles away.
4/15/2008 1:34:23 PM EDT
[#15]

Quoted:
Something similar to this was on TV last night- Dateline or something. About the time it came on the dinner bell rang.


That's the same guy.



Said Kanzius, "venture capitalists, big pharmaceuticals that might want to buy this to tempt me and stop the research, not going to happen. There is no amount of money that can buy me off. You can not put a price on a human life."


[tinfoil] That's why they're making sure he dies quickly. They'll snatch up his research before his body's in the ground and it'll never see the light of day again [/tinfoil]

But here's the rub:



"If we can come up with ways of delivering these particles to the cancer cells, but not to normal cells," Curley said, "this treatment will work. There's not a doubt in my mind. Any kind of cancer, anywhere in the body!"


They're facing the exact same problem that everyone else is, and aren't any closer to solving it. Killing cells isn't the problem; traditional chemo can kill cells just fine. Killing the right cells is what's hard. If you had the mechanism for targeting these gold particles to cancerous cells, you could take the same vector and use it with any number of other chemical or biological cancer cures.

They're giving people false hope. They're claiming they have something that they honestly don't, and the news media is eating it up.

Edited for analogy: If a terrorist strapped up with a bomb needed to be shot directly in the brainstem to prevent him from setting it off, the rest of the world is using a .308, and these people are claiming to have the solution because they're using the new and improved 5.56. But they still don't have any advantage at actually hitting their target. Hitting the target is what matters; what you hit it with can be highly variable.
4/15/2008 2:33:47 PM EDT
[#16]

Quoted:

They're facing the exact same problem that everyone else is, and aren't any closer to solving it. Killing cells isn't the problem; traditional chemo can kill cells just fine. Killing the right cells is what's hard. If you had the mechanism for targeting these gold particles to cancerous cells, you could take the same vector and use it with any number of other chemical or biological cancer cures.


I am more excited about this;


Cleveland BioLabs, Inc. (Nasdaq: CBLI) (Boston Stock Exchange: CFB) today announced that it has completed its analysis of non-human primate trials of its lead radioprotective drug candidate Protectan CBLB502. These trials demonstrated that CBLB502 provides an unprecedented increase in survival among lethally irradiated non- human primates compared with the untreated control group. The trials showed effectiveness in protection against Acute Radiation Syndrome (ARS). ARS is a potentially fatal condition resulting from exposure to radiation from a military attack with a nuclear device, terrorist action, or nuclear accident. Generated results demonstrated that CBLB502 was active against both types of ARS, specifically, hematopoietic and gastro-intestinal syndromes in the primates which suggests that the Company's radioprotectant is activating a broad variety of biological processes contributing to the observed increase in the radio-resistance of mammals.

In these trials, 75% of Rhesus monkeys irradiated with a single 6.5 Gy bilateral whole-body dose of gamma irradiation treated with a single dose of CBLB502 survived the lethal irradiation (compared to only a 25% survival rate in the untreated control group). Half of the surviving primates which received an injection of CBLB502 showed no detectable gross pathological changes 40 days after treatment, and the histology of their lymphoid organs and bone marrow appeared normal. Whereas, all surviving primates from the untreated control group suffered multiple severe abnormalities and injuries. The observed radioprotective efficacy of CBLB502 may be attributed to a rapid and substantial increase in the blood concentration of a number of tissue protecting growth factors and cytokines following its injection.

"We believe that these remarkable results demonstrate the potential of CBLB502 as a powerful radioprotector and represent a significant step towards FDA approval of our radiation antidote candidate for military and civil defense applications," said Michael Fonstein, CEO and President of CBL. He added: "We are equally excited by the lack of gross pathological changes seen in half of the CBLB502-treated animals."
4/15/2008 2:35:13 PM EDT
[#17]
SAVE US WILL SMITH!!1111
4/15/2008 2:42:41 PM EDT
[#18]
They still will have to figure out the correct antibodies for each specific type of cancer.  



Besides, if they cure cancer everyone will just die of heart disease.  




The health nuts will die of alzheiemers.
4/15/2008 2:44:52 PM EDT
[#19]

Quoted:
They still will have to figure out the correct antibodies for each specific type of cancer.  

Besides, if they cure cancer everyone will just die of heart disease.  


The health nuts will die of alzheiemers.


They'd just reverse the effects of aging by the time the cure for cancer comes around.