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Posted: 5/30/2003 10:05:11 AM EDT
[url]http://www.cnn.com/2003/TECH/science/05/30/cloned.mule.ap/index.html[/url] OK, so it was really a mule... WASHINGTON (AP) -- The first member of the horse family to be cloned is a mule named Idaho Gem, the genetic brother of a champion racer. Researchers say two other mule clones are expected to be born this summer. The May 4 birth of Idaho Gem adds mules to the barnyard of cloned animals that already included sheep, cows, pigs, cats and rodents. University of Idaho researchers cloned the mule using a cell from a mule fetus and an egg from a horse. Idaho Gem is the genetic brother of Taz, a champion racing mule, and the researchers said the cloned mule also will be trained to race. Cloning a mule is particularly unusual because such animals, hybrids from a donkey and a horse, are almost without exception sterile and unable to produce young. "A mule can't do it himself, so we thought we would give it a hand," said Gordon L. Woods of the University of Idaho, the leader of the mule cloning team. Cloning horses next? Now, said Woods, he plans to use the same techniques that worked on Idaho Gem to clone horses. "We think the same sort of advances that we had to make to produce this cloned mule are important for cloning horses," said Woods. He is first author of a report appearing Friday in the journal Science. Other researchers, however, said they expect the birth later this year of cloned horses produced by techniques slightly different from that used by the Idaho team. Mules are bred by mating a male donkey with a female horse. The breeding success is about the same as among horses alone. Mating a male horse with a female donkey produces an animal called a hinnie. Both mules and hinnies can be either male or female, but they are almost invariably sterile. Taz, Idaho Gem's brother, is a champion on the mule racing circuit in California and Nevada. Taz has gained fame in showdown races with another mule, Black Ruby, who has dominated the circuit. To clone the racing mule's brother, researchers bred Taz's parents, a jack donkey and a horse mare, and allowed the resulting fetus to grow for 45 days. This provided the DNA needed for the clone. The researchers then harvested eggs from horse mares. After removing the nucleus from each egg, the researchers inserted the DNA from the male fetal cells. The eggs were then placed into the wombs of female horses. Financing the research Donald W. Jacklin, a businessman in Rathdrum, Idaho, paid $400,000 to finance the four-year mule cloning project. "Our first goal was to clone an equine, but I have a special interest in mules," said Jacklin, who is president of the American Mule Racing Association. Since mules usually are sterile, racing mule owners cannot breed new animals from proven race stock to build up their stable as thoroughbred and quarter horse owners do. Mule cloning could offer an answer. For that reason, said Kate Snider of the American Mule Racing Association, "cloning a brother to Taz is a very big deal." Jacklin said there are more 200 members of the mule racing organization and that 70 to 80 mules race each year on a circuit of tracks in California and Nevada. Woods said to clone the mule, he and his researchers bathed the horse eggs in different concentrations of calcium. He said the calcium ratio that has been used for cloning other mammals produced only two pregnancies out of 132 attempts and no births. Higher calcium concentrations had better luck, leading to Idaho Gem and two other full-term pregnancies. Important advance? Also, unlike other researchers, the Idaho team placed the manipulated eggs into the womb without allowing the embryo to grow in a laboratory dish. Experts applauded Woods' success. "This is the first cloned equine, so it is a very important advance," said Katrin Hinrichs, a professor at Texas A&M and the leader of a group of horse cloning researchers. Hinrichs said the result was particularly encouraging because her team is also attempting to clone an equine. She said they used a technique different from Woods, allowing the cloned embryo to grow to a later stage in development before implanting in the womb. Hinrichs said that out of five manipulated eggs, her team has produced one long-term pregnancy and expects a mare to give birth to a cloned horse in November. Hinrichs said she has been told that another group of researchers may clone a horse even sooner. A mare carrying a cloned fetus is expected to deliver in Italy this summer, she said.
Link Posted: 5/30/2003 10:07:46 AM EDT
[img]http://images.southparkstudios.com/media/images/105/4assed_monkey.gif[/img]
Link Posted: 5/30/2003 10:08:49 AM EDT
From the title, I thought that they had cloned Sarah Brady.
Link Posted: 5/30/2003 10:13:22 AM EDT
Stop that! I thought they cloned a Clinton![puke] Are you trying to start a panic? [;)]
Link Posted: 5/30/2003 10:22:25 AM EDT
Originally Posted By Kaesan: Stop that! I thought they cloned a Clinton![puke]
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I see your point. Clinton would be a clone. Sarah Brady would be a Clunt.
Link Posted: 5/30/2003 10:27:15 AM EDT
Originally Posted By piccolo:
Originally Posted By Kaesan: Stop that! I thought they cloned a Clinton![puke]
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I see your point. Clinton would be a clone. Sarah Brady would be a Clunt.
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LMAO "Clunt"!
Link Posted: 5/30/2003 10:32:16 AM EDT
Damnit, that title got me all excited [:D]....I was hoping to maybe even see some pics
Link Posted: 5/30/2003 11:45:23 AM EDT
Some mad scientist stole a hair sample from Bill Clinton's hair brush or did he steal that famous blue dress????
Link Posted: 5/30/2003 11:57:06 AM EDT
[Last Edit: 5/30/2003 11:57:26 AM EDT by Dredd308]
Originally Posted By buffalo-soldier: Damnit, that title got me all excited [:D]....I was hoping to maybe even see some pics
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[img]http://i.cnn.net/cnn/2003/TECH/science/05/30/cloned.mule.ap/story.mule.ap.jpg[/img] There you are!
Link Posted: 5/30/2003 11:58:52 AM EDT
Link Posted: 5/30/2003 12:36:32 PM EDT
[Last Edit: 5/30/2003 12:37:27 PM EDT by ArmdLbrl]
I don't know why they are calling it a clone, it isnt.
The researchers then harvested eggs from horse mares. After removing the nucleus from each egg, the researchers inserted the DNA from the male fetal cells. The eggs were then placed into the wombs of female horses.
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Its a artificial twin. To be a clone, you need to start with a adults DNA and there is no sexual reproduction involved. This is just mechanically replicating what happens accidentally in nature when identical twins occur.
Link Posted: 5/30/2003 3:22:30 PM EDT
Originally Posted By piccolo:
Originally Posted By Kaesan: Stop that! I thought they cloned a Clinton![puke]
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I see your point. Clinton would be a clone. Sarah Brady would be a Clunt.
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[ROFL]
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