Again some excellent advice from the grey man. Amox, cipro, doxy, TMP/SMX, flagyl are all on the walmart $4 list.

I'd second the choice for Amox over PCN. Better dosing schedule, better tasting (in liquid form), reasonable bioavailability.

Re MRSA - TMP/SMX is a reasonable oral alternative and cheap.

Re anaerobic infections - I'd choose flagyl over clinda. Clinda doesn't have reliable activity against b frag - hence clinda above and flagyl below the diaphragm. Flagyl also can tx amebiasis, trich, giardia, c. diff

OK chemist here.

Oxytetracycline is not FDA approved so not used in the USA. It is inferior to Doxy since Oxytetracycline oral absorption is food dependent (variable exposure based on when & what you eat last) and Doxy is not.

You didn't want to know the chemical difference I assume?

PS glad the Doc's showed up, a chemist makes these drugs but I sure as hell don't want to play Doctor.

What about an Oxytetracycline drip?  Any farm kid knows the dosage for swine, and I could run an IV if I had to as long as I knew the correct dosage.

 

Cefdinir.  300mg twice daily for 10 days will take care of a LOT if infections, but you really need a flouroquinolone (Levaquin, Cipro) on hand also.

OK here is my experience with fish antibiotics. I purchased the following from C&Q management or Thomas labs via Amazon.com
Identifying the manufacturer was done by comparing the form provided (capsule or pill) color scheme and markings for each antibiotic by a web search. In each case a photo was found from the manufacturer that matched exactly with what was provided as 'fish antibiotic'. This is not surprising since all of these are now generic and cheap to purchase wholesale. The two sources mentioned simply buy in bulk, repackage and sell direct for use on aquarium fish - perfectly legal under current law.

Note all of the dose forms below are those standard for human dosing

Tetracycline 250 mg made by Teva
Ciprofloxacin  500 mg   made by Ranbaxy
Doxycycline  100 mg made by West-Ward
Cephalexin 500 mg made by West-Ward
Metronidazole 250 & 500 mg made by Pliva
Erythromycin Sterate 250 mg made by Abbott (enteric coated)
Amoxicillin  500 mg made by Davo
Bactrim 800 x 160 mg made by Interpharm

My fish now live secure in the knowledge that come SHTF they are covered.

Why would you consider oxy when doxy is readily available, cheap and has great oral bioavailability?

So you fancy yourself some kind of expert?

I keep forgetting to research these ABx threads and keeping some on hand.  An ounce of prevention and all that.

Because I can get Penicillin and Oxy in 50 gallon drums that will store in a cellar for 25 years.  






 

tagged for very useful info

OK then:
––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Oxytetracycline


NON-FDA APPROVED USES
Granuloma inguinale caused by Calymmatobacterium granulomatis
Lymphogranuloma venereum caused by Chlamydia species; nongonococcal urethritis; chancroid caused by H. ducreyi
Psittacosis caused by Chlamydia psittaci  
Q fever (Coxiella burnetii)
Rickettsial pox; typhus infections
Rocky mountain spotted fever
Relapsing fever caused by Borrelia recurrentis
 Infections caused by B. bacilliformis
Yaws caused by T. pertenue
Infections caused by M. pneumoniae  
Brucellosis
Infections caused by Yersinia pestis and Francisella tularensis  
Soft tissue infections
Vibrio comma and V. fetus infections
In PCN-allergic pts: infections caused by N. gonorrhoeae, T. pallidum and T. pertenue (syphilis and yaws), L. monocytogenes, Clostridium species, B.  anthracis, Fusobacterium fusiforme (Vincent's infection), Actinomyces species.

USUAL ADULT DOSING
Oral: 0.5-1.0 gm PO four times daily.
IM: 0.5-1.0 Gm/day IM q12h.

ADVERSE DRUG REACTIONS

COMMON

GI intolerance (dose-related)
Stained & deformed teeth––children up to 8 yrs
Diarrhea
Phlebitis w/ IV & pain w/ IM injection

OCCASIONAL

Negative nitrogen balance & increased azotemia w/ renal failure
Hepatitis
Esophageal ulcerations
Candidiasis

DRUG INTERACTIONS
Digoxin: may result in increased digoxin concentration
Penicillins: in vitro antagonism when co-administered. Bactericidal effect of penicillins may be diminished in vivo. Avoid co-administration.
Urinary alkalinizers (sodium lactate, sodium bicarbonate): increased urinary excretion of tetracyclines (by approx. 24-65%) resulting in lower serum concentration. Monitor for therapeutic efficacy.
Polyvalent metal cations (aluminum, zinc, magnesium, iron, calcium [milk]) : polyvalent metal cations form an insoluble chelate with tetracyclines resulting in decrease absorption and serum level of tetracyclines. Separate administration by 4 hours.
Bismuth salts (bismuth subsalicylate, Pepto-Bismol): bismuth salts chelate tetracyclines resulting in a decrease absorption of tetracycline. Administer bismuth 2 hours after tetracycline.
Warfarin: may increase hypoprothrombinemia. Monitor INR closely.


SPECTRUM
Aerobic gram-negative bacilli
Acinetobacter baumannii (calcoaceticus)  2nd line
Actinobacillus actinomycetemcomitans 2nd line

Anaerobic gram-positive bacilli
Actinomyces israelii     2nd line
Actinomyces naeslundii     2nd line
Actinomyces odontolyticus    2nd line
Arachnia propionica     2nd line

Miscellaneous
Afipia felis     1st line

Mycobacteria
Mycobacterium ulcerans     2nd line


PHARMACOKINETIC PARAMETERS

Absorption: 60%
Metabolism and Excretion: Only small amount metabolized in the liver. Significant amount excreted via biliary route. 60% excreted unchanged in the urine.
Protein Binding: 27-35%
Cmax, Cmin, and AUC: 4 mcg/ml after 500 mg PO dose administration.
T1/2: 6-10 hrs
Distribution: Poor CNS penetration. Good biliary concentrations. Inadequate middle ear fluid concentration.

If you're up for this, I'd be interested in the info.  I just found - and ordered - a used copy of that book but wouldn't mind a jump on the info since, um, my fish seem a little under the weather and I'm getting ready to order some meds soon.  IM me if more appropriate.

BlackFox, I would like this info also.

For the life of me I wish this thread were tacked. TONS of very good info found within. Thanks to the contributors!



ETA Blackfox, me too!! (please)

Add Cephalexin (Keflex) to this list and you're good.

I've had a few bouts of diverticulaitus (sp?) over the years, and this is the only thing that would touch it. If I eat right and add fiber I'm good to go. But this is a MUST for my preps.



 

MODS: I believe this material is okay to post, but please IM me or delete if not.  Adventure Medical posted it on their website as a publically downloadable pdf.  I'm just putting it here for convenience sake. It's also hard to put a hard-copy book into an electronic portable device .  

Source: A Comprehensive Guide to Wilderness & Travel Medicine
by Eric A. Weiss, MD
Amazon Link

ANTIBIOTICS

Some of the antibiotics listed below have similar uses and overallping spectrums of antibacterial activity.  Before departing on your trip, discuss with your physician which antiobiotics best suit your needs.

Azithromycin (Zithromax) 250mg capsules
This is a broad-spectrum, erythromycin-type antibiotic.  It is more potent than erythromycin, causes fewer side-effects, and only has to be taken once a day for five days.  


Amoxicillin Clavulanate (Augmentin) 500mg tablets
A broad-spectrum penicillin-type antibiotic.  


Ciprofloxacin (Cipro) 500mg capsules
An excellent antibiotic for traveler's diarrhea and dysentary.  


Erythromycin 250mg/500mg tablets
An alternative antibiotic for individuals allergic to penecillin.  


Cefuroxime (Ceftin) or Cephalexin (Keflex) 250 to 500 mg tablets
Broad-spectrum antibiotics which can be substituted for Augmentin, in individuals allergic to penecillin.  


Metronidazole (Flagyl) 250 mg tablets


Nitazoxanide (alinia) 500 mg tablets


Trimethodprim / Sulfamethoxazole
Common brand names include Septra DS and Bactrim DS.  Each tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.


Levofloxacin (Levaquin) 500mg tablets


Cortisporin Otic Suspension


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Please forgive any typos (and let me know about them) - I manually transcribed this.

By the way, if I understand our new health care gift from our overlords - imported medications are about to spike up quite a bit next year (if not sooner).  

GD Link to healthcare timeline

Consider natural antibiotics as well.

Oil of oregano is a natural antibiotic and anti-parasite.  It's strong stuff, usually comes as a liquid and has a dropper.

Colloidial Silver is another natural anti-biotic and can be used to purify water.  Also a liquid.

Both should be used sparingly as they are quite strong and widely available without perscription (for now) in many health food stores.

Yep... argyria for the win.

Will you write me scripts for each of those, doc?


j/k... Thanks for the info.  I've been meaning to get some for our stash too.

Reading is fundamental:

"Both should be used sparingly as they are quite strong and widely available without perscription (for now) in many health food stores."


You'd have to take in quite a bit to become the blue-man.  You wouldn't do that with Rx anti-biotics and you shouldn't with natural stuff either.  Comon sense rules the day.

Can you find me any data on what level of exposure to colloidal silver will cause Argyia?  Cause I can't find anything. Nor has it's use been shown effecitve at treating anything.

Would be very interested on your thoughts in regards to adding Cephalexin to your list for treatment of wounds.  
Staving off infection from lacerations, punctures etc.

I've been Rx'd that stuff for all kinds of wounds and procedures.
Particularly abcess type indications.
Seems like a goto for that sort of thing.

Get This:
(but get the latest year, obviously)

Ah, Sanford-and-Son... a classic.

ETA: to answer the post above P-Smith's... Keflex (Cephalexin) is just more gram-positive coverage, like the amoxicillin.  It may cover a bit more, but it's a beta-lactam antibiotic, just like the penicillins.  There isn't much difference in the coverage spectrum from an amino-penicillin (like Amoxicillin) and a first-generation cephalosporin (Keflex).  In fact, a bacteria resistant to penicillins is likely to be resistant to a first-gen cephalosporin as well... since the beta-lactamase enzyme that protects the bacteria will attack the beta-lactam ring that both antibiotics possess.

tag

So is there a consensus on the shelf life of these under ideal conditions?

Tag for cutting and pasting some of this info into a chart

Duggan,
here is a link where you can get Zithro......just received mine yesterday from them.     https://alldaychemist.com/906_Zithromax-500-mg

A BIG thank you to everyone who posted information for those of us not trained in the medical profession.  I salute all of you who share your knowledge with us, not just about this topic but other in
the SF.  I hope in the future I will have gained the necessary training and experience to post helpful information for others as all of you have.  Again, thanks everyone!!  Forgive me if I didn't post this correctly?!

Redundant, got it.  

Thanks GrayMan

There is some good info in this thread. Thanks to all who have contributed.

Raw Crushed Garlic

That and Prozac.

tag



 

Or less-than-ideal conditions?



Seems kinda useless to stock up on antibiotics if they are useless/toxic in six months.



 

Store them in air tight containers in your freezer and they will last 10 years.

Does that apply to all of the ones you listed, or just some?  Thanks.

Sanford's is a classic, but I like the John Hopkins guide a bit betterAmazon link  They also have a free website you can use with a computer (can't use it with smart phone)

All of the oral antibiotics will store well if kept dry, out of light and as cold as you can get them. I am unaware of any (oral) antibiotics that have less than the default 1 year shelf life. Most would be fine for several years if stored in an airtight container in the dark. Stored at -10 or so will at least triple the shelf life. I have some going on 20 years that I know for a fact are still OK.

I'm curious how you know theyre ok.  And by ok to you simply mean non-toxic? Or are they still efficacious?

Well since 1981 I have been designing and synthesizing new drugs at a major pharma company (first ten years antibiotics). Out of curiosity I did an HPLC and NMR analysis on an old batch of pen-g I had, no significant decomposition observed.

Tag.

Not many people would have the expertise much less the facilities to do that type of testing. What others have you tested to see their degredation?

Of my own personal stash? That was the only one and I did it more on a lark than out of concern.

Of all the classes of antibiotics the beta lactams (penicillins) are at or near the bottom for chemical stability. The fact that this sample had little degradation speaks strongly to how well antibiotics (and most pharmaceuticals in general) will last if stored under the best conditions. Had it been sitting on a shelf in less than an air tight container the result would be much different.

Remember to keep in perspective what we are discussing here, storing pharmaceuticals for a worst case scenario - no access to proper medical care in a emergency. This includes chronic life threatening diseases like diabetes.
No one, I hope, is amassing stockpiles to be used under normal circumstances. If your sick go to the doctor for treatment not a best guess from your stash.

The hard part of practicing medicine is not deciding what drug to prescribe, it's deciding what disease the patient has. That, my friend, is what all that training is for and what you and I don't have.

CDC and DOD routinely test drugs for long term stability.  And they won't tell you the answers, since they only apply with 100% certanty to that batch of drugs satored under the conditions they were stored in.  In general it seems they almost never find stuff to go bad (go bad, being defined as reaching 90%of labeled strength).  This is all sealed products in conditioned air or ref storage with continious monitoring.

As far as antibiotics, the common ones stored in conditioned space are cipro, amoxicillin, and doxycycline, most of the other stuff in in refregerated storage.  Most states have 3-5 day supplies of these drugs uinder their control for rapid release to medical, public health, and first responders.  One state stores them in a locked cabinet at all of the state trooper stations.

One of my favorite intensivists used to say in his thick Irish accent "my recurring nightmare is that I'll be laying sick in some ICU bed someday, and I'll look up, there'll be an intern looking through a copy of Sanford's, and then, at that moment, I'll know I'm foooked."

 Useful book though.

get drugs to deal with parasites....they will be much more likely when TSHTF.