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How long is the barrel and what is the twist rate?
The Ramshot burn rate chart shows 4000-MR as slower than Reloader-22, a magnum powder.
It would physically work and might even be decent in a longer barrel with a heavier bullet. For example, a 190 SMK or a 210 gr Berger in a 26" to 30" barrel. These bullets need a 1/10 twist.
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I do like Western (Ramshot) powder comparison chart and find it quite useful.
The older thread I found last night before turning-in had reloaders picking the Alliant engineer's head looking for pressure data on the then new 4000-MR and several reloaders all came to a loose
consensus that had 4000-MR coming right in between RL-19 and RL-17 with several strongly comparing 4000-MR to RL-17 in most aspects.
Now if Alliant can test 6.5CRM with 140gr boat-tail bullets with RL-16 powder and Speer can test 6.5CRM with 140gr boat-tail bullets with 4000-MR I'm wondering if the between RL-19 and RL-17
observation has validity.
Only way to find out is to run a few loads over the chrony.