Bullet weight can have tremendous effect on point of impact, compared to "standard weight" bullets, lighter bullets impact lower on the target, heavier bullets impact higher.
Long ago when I was a Deputy we carried 357 revolvers, my S&W model 66 was sighted in perfectly at 25 yards with the standard 158 gr bullet. Then the hot item was the high velocity 125 gr HP's, actual ballistic results from shootings showed it had the best terminal performance of any standard revolver caliber.
One BIG problem, they shot low, really low, at 25 yards the impact was off the standard B27 man sized target, the sights on my model 66 couldn't even be adjusted to bring it to point of aim at 25 yards, as I recall, best sight adjustment was about a foot low at 25 yards, at closer ranges it wasn't as big a problem, but as long as I carried that load I had to remember to use Kentucky windage if the range approached 25 yards. Not a very good situation overall.