Spill any powder? Sometimes that'll walk all the way around and deposit in the primer cup and dent your primers. With no case on the station, simply push the handle as seating a primer and look at/wipe off the primer seater. Spilled powder can also land on the primer shuttle and interfere with it's movement. Make sure your primer cup doesn't rub on any of the shellplate holes. A slight rub on the shellplate can flip a primer when it momentarily catches and releases. BTDT. Check all the holes in the plate as they'll occasionally make one with a hole out of alignment. BTDT too.
The powder settling down is normal for most, especially flakes. A lot of times I'll throw a half dozen just dumping them back in the measure doing nothing with them. Then I'll measure one to check to see if it's on where I want to be. Then I'll throw ten and dump them all in the same pan and see if the charge is the same with the decimal moved one place obviously. Then I'll check a few more singles and make sure I'm not getting a randomness. Then i load a few checking charges on each, be very careful to put the charge back in the empty case and not double charge anything. I be super duper deliberate carefull when you're interrupting the work flow. Know what the correct charge looks like and know what a double looks like. I look in every case after it's filled by hovering over that station.
my technique once stations are all full is to set the bullet on station 3, put a case in station one, cycle handle sizing, watching the primer shuttle and seeing a primer in the cup, watching the powder bar activate, lower handle, while peeking in on the powder fill at station 2 and seating the primer. cycle the shellplate. The most important thing is watch the powder bar and check the dropped charge by eye. if there is ever any stoppage for any reason that affects the powder bar movement, i'd weigh it to be sure. For the dillon I like to load with powder that can't be double charged without overfilling or at least be right up near the top. Make it obvious. I'd rather clean the press than get eye surgery.