Personally, if it was mine and I was going to use it for self-defense, I’d take the screw out and be done with it. Any benefit is far outweighed by the possibility of it getting out of adjustment and taking the pistol out of commission.
Don’t know if it’s true, but I was told quite a few years ago that a LEO lost his life in a gunfight after the trigger stop on his S&W revolver (same concept) got loose and bound up his revolver. I do know that we had to go through all the revolvers where I worked at the time and remove all the stops.
Keep in mind this screw butts up against the magazine catch. If you swap out the magazine catch for any reason, it’s a good idea to recheck the screw setting.
I read recently that supposedly some rifle competition shooters are getting away from the trigger stop concept, feeling that having the trigger abruptly stop immediately after tripping the striker actually induces a little bit of a jerk. Apparently they’d prefer the trigger to continue backwards a ways. I don’t know if the concept would also apply to handguns.