I first bought a DE 357 then upgraded it to a 50AE. It eats at ya knowing this monster hanggun is capable of much more than a "puny" 357 magnum round. If you're gonna spend the dough on a Desert Eagle ($800-$1400), then the $1.10 a shot shouldn't bother you too much. Go big. That's the Magnum Research way. Big. You don't buy a Desert Eagle to conceal. You buy it either to hunt or target shoot. I guess if you're eccentric and have the nickname of 'Boomer,' carry it on your hip.
Don't get me wrong, it's probably my favorite handgun, and was also my 'first.' Gun that is.
My experience is that there are THREE things that'll interfere with your shooting regarding the Desert Eagle, of any caliber.
1) Bad ammo
2) Loose grip on the gun
3) Bracing the gun by magazine
Magnum Research recommends certain types of ammo as the slide is heavy and needs a good flame to push it back. I thought I could get away with some plinking 357 rounds, but they kept jamming. I switche to MR's recommended ammo, and no problems thereafter.
Also, the torque on the extractor is more powerful than most. Especially with the .50AE, so a firm grip is necessary to prevent the bolt moving you instead of the spent casing. You'll know this when the first one bounces off your face.
Also know that you should not hold the gun by the base. Any pressure on the free-floating magazine will cause it to jam. This cause a whole mess of problems. And is, according to Magnum Research (I called) is the most common problem owners complain about. Simple fix.
It seems finicky but if you follow those 3 rules (again this is just my experience) you'll have a good time, with any caliber.
Another point of note, some people like the gun and some don't. The fact is that the Desert Eagle is a big powerful semi-auto handcannon. It's made for blowing out big rounds. It takes some finesse. The gun has it's limitations, but that's not why we love em so much now is it! If I want to carry a gun or shoot something hostile, chances are I'd unholster my glock or my 1911. Unless of course the Desert Eagle .50 Action Express is already in my hands, in which case I'd blast the target into the next grid and mop up the goo later.
You should see what that .50 bullet does to an eggplant. lol. But if you're gonna get a Desert Eagle, go for the grizzly. Go 50AE. The thing weighs 4.5 lbs empty. It's made for 325 grain loads. Use it. Although in defense of the 357 magnum barrel option, the recoil is similar to that of a 9mm.
Happy shooting