Ok let me throw some stuff out FWIW I might be right or wrong
1) Glock 29 is too small to hunt with unless you get a 6" barrel, that will look just goofy.
2) If you are looking at getting a Glock 29/20 combo they WILL cover self defense and hunting tasks quite nicely.
3) The Glock's in 10 mm are the only stock guns (10 mm) up to the beating that round can roll out.
4) Most 10 mm rounds are signifigantly less "zippy" than the original loadings. SO the recoil etc. probably won't be as bad as expected.
5) There are still full power 10 mm loads avail. IF you absolutley need to put a hole through something either sporting or defensive......
On the other hand .45 is nice too, and ammo is probably cheaper and easier to come by.
I had a G-21 for about 2 years before gettting a G-30. Initially I found it a little brisk to shoot. I got used to it, and it's really nice now.