I have one in 40, I use it for a range gun only. It has a long trigger pull and I do mean long, you can get used to it if you try, but it is difficult. I shoot revolvers, DAO autos and SA/DA autos, I find it hard to shoot these and then go to the 100 - the trigger pull is so long that I frequently end up "pushing" the muzzle down as I squeeze the trigger and just can't stop myself from expecting to hear a "bang". If you just shoot revolvers or will shoot the 100 predominately you can do well I think, but going back and forth will cost you accuracy. If you are thinking of this for CCW or personal protection: the front sight is an intergral part of the barrel so night sights are out/the 40 is ported/to my knowledge there are no hi caps for this gun. I don't think the recoil spring for the 40 is strong enough and there are no aftermarket springs.
The pluses are that it is accurate, when the shooter doesn't screw up (aka me). Mine is very well put together. The grip fits me well and the sight radius is excellent. It is a snap to field strip. Holsters used to be a problem but more are coming on line. I bought mine over two years ago and I plan on keeping it.
Hope that helps.