Ive never shot a American Western Arms saa but i do have a lot of experience with rugers and colts.....
The Vaquero has a fatter grip than the SSA so it handles recoil a bit better. To me shooting a 250Gr flat nose in a Vaquero feels like shooting a 200Gr flat nose in an SSA.
aka very mild
The SAA also has a bigger ejection rod knob than the Vaquero. IMO Ruger messed up when they put that tiny stud on the end of the rod. Eject a few hundred rounds on a Vaquero and you will know what i mean.
Another quirk about the vaquero's is their cylinder indexing.
On an SSA or clone the timing notches are right on the money with the loading gate when extracting empties.
On a Vaquero you have to move the cylinder in between notches to line it up with the gate to extract a shell.
A minor pain in the ass but you do notice it.
Then theres the action and trigger.
On a true well built SSA (not necessarily the cowboy) It about as smooth and crisp as it gets. The best way i can describe a vaquero is dull and mushy.
yes you are paying a bit for the name. Yes SAA's do need tune ups versus the maintenance free vaquero.
But hey I'm comparing a Rolex to a Timex here.
One has changed very little in the past 130+ years the other has so many lawyer proof things built in its almost a pain.
My advise is get one of each
photo left to right top to bottom1. 38 WCF colt SAA with colt custom shop grips made in 1995
2. limited edition ruger vaquero 45 colt with 45 acp conversion cylinder
3. 45 colt SAA made in 1978
4. 45 colt vaquero with optional fake plastic ivory looking grips