I don't know what kind of use my SW Model Ten saw before I got it, but in the last three years it's seen just a tad more than 50,000 in my hands, and it's still tight. It's missing a lot of its blueing, and it never was the prettiest gun made, when it came out of the factory in the early 60's. Mine had the pencil barrel, pinned, but the chambers are not recessed. And the ammo is nearly all full-power reloads, I developed a serious bowling pin addiction several years ago, and fired over 30K in ONE YEAR before my budget constraints finally caught up with me. All I did for a year was shoot, clean guns, and load ammo. It was a good year!
Oh, my gun did break a firing pin at about 46.050 rounds. It was shooting again in a week. Like I said, I don't know how much it was shot before it was issued to me, but there isn't a whole lot of rifling left in the barrel, I only shoot plated bullets.
And a Ruger is overbuilt to the point that I don't think you could wear it out unless you beat it to death with massive overloads, and it would STILL take a long time. As has been said, if you can wreck a Ruger, handloading ammo is NOT for you.
Papajohn