I think in a well designed and constructed pistol/guide rod we are talking about the >1% difference in longevity/performance. The correct polymer and design can seem indestructible. I can tell you first hand that in Afghanistan there were several S&W 9mm pistols with broken guide rods that caused them to be unservicable. Maybe it was the type of polymer, maybe the design, or maybe both played into that.
I am sure some of you are familiar with
the 1,000 round glock G19 torture test in which the plastic guide rod melted off. I've taken some high round count classes and never got close to melting a guide rod.
My go to Beretta runs a
Wilson Combat fluted Guide rod.
I have personally seen far more problems with plastic guide rods than metal ones. That's my first hand experience. BTW, both my normal concealed carry guns run plastic guide rods (Gen3 G19, XDs 3.3).