Would consider thread locking compound after an initial trial run for the summer (always nice to know everyhting works first and you really like your Aimpoint with this spacer etc.).
In the old days (20+ years ago), used new screws and new mounts on many large caliber rifles and had very good luck holding on many installation removing all oil with solvent (i.e. Gun Scrubber now days) and setting the screws near max (maybe with a tap or two on the driver). However, these screws are actually harder to remove than many of screws put in with thread locking compound due to the metal to metal contact (one or two had to be drilled out .. ouch!).
On side note, stepping foward in time, my brother always specs thread locking compound in the tooling and equipment he designs to make removal easier (also acts to protect the threads from rust) and assembly more constant (thread lock compound tends to be a thread lube when wet).