There's the advantage of practicing with your actual fighting sights, which should of course be luminous, another $100 saved as vs the .22 upper. ditto if you use an optical sight. You must not use an upper with a Ciener .22 unit as its guts, because it's WORSE to change out than the .22 unit in a 223 upper. I have a Kuehl Precision upper, and it requires that the 22 unit's recoil spring be "loose", instead of held captive like it is on the 22 unit, when using the chamber insert and the 223 barrel.
I already said what the main advantage is. You don't have to lug around a bulky, 4 lb upper in order to have the option of either the 223 or the .22lr. All you have to have is the 22 unit and a magazine, wrapped in a gun cleaning cloth, in the thigh pocket of your pants.