Just be careful when you start using terms like "published" load data. There is very little actual published, pressure-tested data out there, most notably a little from Barnes and Accurate Powders. The vast majority of load data you see is actually somebodies QuickLOAD results, which are not to be taken as gospel in my opinion. Accurate has data for a 300 grain bullet with A 2200 powder so you might check that out.
There is no pressure-tested data for a 300 grain jacketed lead bullet with Reloder 7, but it is a very forgiving powder in the Socom. You can certainly drop down to around 38 grains with no ill effects, the main problem you might run into is excessive soot and unburned powder grains. Most people work up to "max" loads and then settle on a mid-range load they like, so there isn't a whole lot of information out there concerning reduced loads that are still supersonic. Subsonic loads with heavy bullets, you bet, but not so much for reduced loads.