I am a theoretical fan of the AR-10, and a practical fan of the AR-15.
There is no circumventing the price for a QUALITY AR-10 other than buying an Eagle Arms, because all other competitors are IMO cheap and/or without years of experiency in AR-10 manufacturing. If cost/quality is the concern then you have no business getting an AR-10 (get a good FAL). Armalite, the forerunner of the AR-10 has an outstanding warranty policy which if you watch the AR-10 forums you need because Many many rifles go back to the shop at least once for something.
Having said that you need three critical elements to pursue the AR-10
1. A good use for 7.62 over other rounds (A love for the BANG, may suffice so long as the reason is good to you)
2. A specific attraction/obsession with the AR-10. I can accept that a tweaked AR-10 could outshoot the hell out of it's competition in the 7.62/.308 market, but there are more reliable AND far less expensive designs that will outshoot most of us as they are.
3. $$$$ If you are going to do an AR-10 it has to be done right which means (today at least) an Eagle Arms or an Armalite. One is pricey, albeit reasonable, the other is shocking (but the warranty makes up for some of that). Then you have to factor in mag and part costs etc. So love and $ for this specific platform is required
If you don't have all three of these I suggest an AR-15 and/or a FAL. Hell if you do it right you can probably come in around the price of an AR-10 for both the AR & FAL!!!