CR2s are about 1.5mm smaller in diameter and 7mm shorter than CR123s. You may be able to purchase or fabricate an adapter that would let you use them in a CR123 light. It seems that it would not be difficult to wrap electrical tape around the middle of a CR2 to bring the diameter up to ~17mm and then use something like a 3/8" piece of polished aluminum 7mm long (or 14mm long for a 2x CR123 light) and wrapped with electrical tape around its circumference to insulate and center it in the light's bore. (You'd want to be very careful not to short these batteries-- there's a pretty good amount of energy in one.
You can look at the technical specs for each battery (including dimensions)
here at Sanyo's website. CR2s are 850mAH batteries as opposed to the 1400mAH that a CR123 puts out, so you'll get less burn time from a CR2. The CR2s are also only rated for a continuous 1000mA current draw whereas CR123s are rated at 1500mA. Plenty of LED-based lights can draw 1000mA or more, and I'm pretty sure the brighter incandescent lights like Surefires run more than that, too. (Flashlight gurus correct me on this if I'm wrong.)
As an aside, Nikon makes a CR2 adapter that allows you to use three CR2s in place of the standard EN-EL3 and EN-EL3A Li-Ion batteries in the D70 and D70S cameras, so if you happen to have one of these cameras you can also use them in it. The adapter shipped with the D70 but not with the D70S.
ETA: In the thread linked by Skibane above there's a link provided to
this CR2 light at DealExtreme. I haven't used this light, but I did buy a pair of cheap 1x AA Cree lights from them. Mine are a bit rough so far as fit and finish goes, but they work fine and were a great deal.