Like any other GD question, the answer is "it depends". I use 100LL in everything that doesn't have have a converter. I use it in my Hussy mower, my chipper, my chainsaws (with oil), my weedwacker (with oil). my. pressure washer, my Case skidsteer, my plate compacter, and my jumping jack. Oh, yeah, and the airplane. Are you going to start your generator every month without fail? If so, I think 100LL is a waste. Will it sit around for a few months of good weather? Then I would do it. It's the closest to the old time gas small engines were designed for. Planes sit for weeks or months of inactivity. The tubing, which will include some rubber compound tubing or fittings, rarely go bad because of exposure to the fuel. They may deteriorate, but they would have deteriorated at about the same rate if they sat on a dealer's shelf in a plastic bag.
I have never heard of an aviation accident caused by bad fuel. Yes, water gets in the gas, and foreign material can wind up in tanks and block plumbing, but I've never heard of a problem caused by the degradation of the fuel itself. Most of the fuel-related aviation accidents are caused when it stops flowing.
100LL does have lead in it, and a lot of it. It has four times the lead of the gas that it replaced. In our feel good world, they addressed that issue by calling it 100 Octane Low Lead. It may foul spark plugs, especially if the plugs are lower in the combustion chamber. The lower plugs in horizontal opposed engines often wind up with little lead BBs surrounding the electrode. If that's a problem, add a little tricresyl phosphate to the gas, and it will be fine.