I've never shot the S2, but I have shot the others.
DXT: Nice shooting bow, I'm probably being a little picky but it felt a little short for me with my draw length(29" draw) and I shoot without a loop so I was worried about nock pinch.
Drenaline: A little faster than the SBXT but not near as comfy for me. Seemed to have a little more shock, maybe not quite as smooth.
Switchback XT: My favorite of the group, so I bought one. I know there are many bows out there with more fps, but it was very smooth, quiet, and reliable.
Speed is great, but so is being able to shoot without the fears of rotator cuff and shoulder problems. I've had and shot many other brands, but I've really enjoyed my SBXT.
I know everyone is different so the best thing is to try them all and see what you like the best. I know a shorter draw shooter who raves about his DXT.
Good luck, let us know what you get.