I may not be in the know, but I have Marlin 795. It's pretty darn accurate, lightweight (4.5# i think), and about $105. 2" groups at 50' with me driving, so I'm sure it can do better with a decent shooter.
We also have a ruger 10/22. I personally like my marlin better. There are far more aftermarket accessories for the 10/22 if that's your thing.
Heh, forgot about the pistol vs. rifle bit. Don't have a 22 pistol. Shot a 22/45 a bunch, and it's pretty nice. if you have a favored handgun, check and see if there's a 22 conversion kit for it (1911, glock, cz for sure have them, others might also) so you can feel more comfortable with your piece. Walther now makes a P22 that's almost the same as a P99.
Ruger has a $20 rebate on 22 pistols through the end of the year as well, btw.