With a diesel, maintenance is everything. Poorly maintained you will be lucky to get 100,000.... properly a half millon is easy.
See if you can find maintenance records. Ask the owner what intervals they did services at and what brand filters they used.
There is a whole word of difference in fuel filter quality for one, quality filters will keep out much smaller contaminates, thereby extending the life of the fuel system. If you see the cheapest filter made on the system that is a warning.
There are two kinds of diesel owners, those who take pride in thier trucks and go the extra mile to maintain them, and those who abuse the hell out of thier machines. Look for the former, is he is he will talk your head off about the machine.
A third option is do what I did. For my work van I purchased a Ford E-350 diesel with a blown engine. I then had it rebuilt properly so i kneew what I had. 250K miles (almost all fully loaded, over half with a trailer) later my most serious failure has been a few glow plugs and a starter (that didn't get replaced when the engine did). I use quality componets, quality CLEAN fuel, the best filters, syntehtic oil, and am religous about maintenance. The van is getting close to 20 years old and teh engine has over a quarter million miles on it and I wouldn't think twice about jumping into it and heading across country.