If you like historical stuff, in Parkersburg take the boat ride to Blennerhassett State Park, it opens for the season first of May. The mansion has been rebuilt as it was at the time of Aaron Burr using it as a base to start a new country West of the Ohio River. Sternwheel boat ride 5 miles from Parkersburg to the island, and a walking tour around the island. There is also a Blennerhassett museum in Parkersburg. Overlooking the island is Ft Boreman Park, that protected Parkersburg from the Confederate sympathizers on the South side of the Little Kanawha River. Ft Boreman was to keep the railroad bridge across the Ohio River open for traffic; it's on a high hill where you can see all of lower Parkersburg.
Up the river 15 miles is Marietta, the first settlement in the west in the late 1700's. Campus Martius Museum is on the site of the first settlement, and is built over some of the original wall and blockhouse protecting the settlement from the natives.
A couple hours North for you is Moundsville, where you can tour the old penitentiary that was built in the 1860's and used through the 1980's. If you liked the asylum tour in Weston the penitentiary tour is better. There is an overnight paranormal tour that's interesting - you get a 90 minute guided tour of the prison, then are turned lose to wander wherever you want for the rest of the night. Ghost hunter types really enjoy this.