I also work north of the city and moved from NoVA.
1. Got kids? Some of my highly-educated co-workers regret letting their potential tax bill weigh more heavily than the quality of the school district. I don't want to crap on other counties, so I'll just say they're in "not Albemarle."
2. Don't commute an hour to work, it's just not necessary to do that to find that acreage and price range. You might look out toward Stanardsville. One co-worker has 5 or 10 acres, but his property abuts the GW Nat'l Forest, so for shooting and hunting, it's like he has a million.
A funny thing happened when we moved here. It used to take longer to get to Wegman's in the same town (Woodbridge) than it does for us to get to the one here, but now we don't go because it's "too far away." In congested areas, our perception of distance was actually a function of time. Not so here. I have one co-worker who lives in Madison and he might as well live on Mars, even though his commute is much faster than mine used to be from Woodbridge to Herndon. The NoVA urge to "run away!!" just doesn't apply here the way it does up there. You can live 15-20 minutes from work and still live some place where you can shoot off your back porch.
If you're not coming to stay long, consider renting. The houses near me seem to go on the market for several months, then go off, then back on again with another agent. Some of them were for sale when we bought 6 1/2 years ago, and they still are, leading me to think that it's difficult to sell a house here. In a hot market you'd see that and wonder what's wrong with the house. Here it may be rather overpriced, (our agent said, "people here sure think highly of their homes,") but the properties are nice. New construction has resumed, so I suspect older houses, especially more modest ones, are a challenge to move. Except in cramped developments, you won't find HOAs, and in the areas zoned "rural area," houses aren't arranged according to any sort of plan. People bought land and built around the modest homes that were in the boondocks when they were built. Our middle-class type house (5/3.5) lies between a tiny bungalow and a giant mansion. We're lucky that our "average Joe" neighbors are good people, but not everyone I work with has been so lucky.
This area is growing, but retail seems to have had mixed results, and industry and commercial corporate centers are virtually non-existent. I suspect that planning rules make Charlottesville/Albemarle business-unfriendly. Many new chain stores seemingly only get approval if they're built in this sort of above ground but "subterranean" style. By that I mean they're surrounded by huge berms and have no signs to let you know they're even there. Even the Wal-Mart, which is not new, is slightly elevated and set back far. There's a Lowe's, but you'd never know if you weren't looking for it. Access to the the stores from 29 tends to be poor, borderline retarded. I find myself having to drive through other stores' parking lots to get where I'm going, and thinking, "this can't be right." To get to the new CVS from any direction but southbound 29, for example, you have to drive through the tiny, cramped lot where Albemarle County Firearms is, then pull a three-point turn to get to the drive-through. It appears to be some stupid plan to maintain the country living feel at the expense of actually being able to earn a living here.
3. Another thumbs up for Martha Jefferson. We've used both systems with no major complaints, but a lot of the practices now part of the UVA system have that sort of "managed care" feel, where you go to a practice, not a doctor. I got excellent service and care at the Profitt Rd emergency room, with prompt transfer to MJH for surgery. MJH is a beautiful facility and you don't have to contend with anything that might be going on around the campus (football & basketball games, commencement, rallies, riots...) I use an independent practice for primary care and am satisfied with it. Similarly, my specialists have privileges with the hospitals but their practices have not come under their umbrellas. (ETA: I'm a former hospital administrator, civilian and military, and I hold healthcare to a high standard. MJH passes my test easily.)
4. The pay cut coming from NoVA may hurt, depending on how you're doing now. Plan for it. Since it's a fact of living here, I go back to #2: give yourself a "raise" in quality of life terms. Cut your commute by half or more, and enjoy a life you couldn't have in the NCR unless you lived 2-3 hours from work.
If you're bringing a good job with you, this is a great place to live. Here, you can actually live a life beyond work and the commute.