South from Montrose to Ridgway. Beautiful scenery, parts of the original True Grit were filmed in and around the area. Go a bit west of Ridgway for a super view of Mt. Sneffels and the Sneffels range at the Dallas Divide. You can continue to Telluride from there. Also from Ridgway, go east up Owl Creek Pass road. Just below the top you'll see a large meadow with Chimney Rock and Courthouse Mountain at the back. The meadow is where the True Grit scene of Rooster Cogburn charging Ned Pepper and his gang was filmed. Just over the top of the pass is the Forks of the Cimarron, and Silver Jack reservoir. More eye popping scenery.
From Ridgway, go south about ten miles to Ouray. It's the Switzerland of America, so they like to say. I'll let others say all the things to see and do there.
On south from Ouray is the Million Dollar Highway and Red Mountain Pass. Below that you'll hit Silverton. Continue on and you'll reach Durango.
Hanging Lake is an example of how Colorado is being loved to death. If you go there, follow all sign directions, and STAY OFF THE LOG and OUT OF THE LAKE.